Quality of Life in Patients With Variant Syndromes of Autoimmune Liver Diseases—A Cross‐Sectional Multicentre Study

Natalie Uhlenbusch, R. J. M. Snijders, Meike Mund, Maciej K. Janik, Piotr Milkiewicz, Bernd Löwe, Claudia Kroll, Joanna Raszeja‐Wyszomirska, Alessio Gerussi, Francesca Bolis, L. Cristoferi, P. Invernizzi, Patrícia Kováts, M. Papp, Lisbet Grønbæk, Henning Grønbæk, E. T. T. L. Tjwa, Luise Aamann, Henriette Ytting, Vincenzo Ronca, Kathryn Olsen, Ye Htun Oo, Adriaan J. van der Meer, João Madaleno, Bernardo Canhão, Bastian Engel, Alejandro Campos-Murguía, Richard Taubert, Özgür M. Koc, Matthijs Kramer, José A. Willemse, Ansgar W. Lohse, Joost P. H. Drenth, Tom J G Gevers, Christoph Schramm

Patients with variant syndromes of autoimmune liver diseases show high physical and mental burden, with fatigue as the main contributor. Particularly PSC-AIH goes along with more severely reduced HRQOL compared to the cholestatic liver disease alone, which is attributable to a higher symptom burden.