Peer Reviewed Journal
Reducing contrast media dosage for pulmonary embolism CTPA in PCD-CT: a comparative study of EID-CT and PCD-CT in the era of individualized protocolling
Authors
Lion Stammen, Eva J I Hoeijmakers, Thomas Flohr, Hester A. Gietema, Janneke Vandewall, Joachim E. Wildberger, Cécile R. L. P. N. Jeukens, Bibi Martens
Citation
Lion Stammen, E. (2025). Reducing contrast media dosage for pulmonary embolism CTPA in PCD-CT: a comparative study of EID-CT and PCD-CT in the era of individualized protocolling. European Radiology. https://doi.org/10.1007/s00330-025-12054-6
Abstract
Question The feasibility of CM reduction in PCD-CT vs EID-CT with highly individualized CM protocols, while maintaining diagnostic IQ. Findings PCD-CT reduces total iodine load by 26.7% and CT dose index volume by 24.4% compared to EID-CT, with comparable objective and subjective diagnostic IQ. Clinical relevance This approach enables CM reduction, potentially lowering patient risk and providing environmental and financial benefits. Additionally, PCD-CT allows for CM and radiation dose reduction while maintaining comparable IQ.