Peer Reviewed Journal
Loss of Skeletal Muscle Mass Is Associated With Reduced Cytotoxic T Cell Abundance and Poor Survival in Advanced Lung Cancer
Authors
Xin Nie, Yan Sun, David P.J. van Dijk, Min Deng, Ralph Brecheisen, Zhaoqi Wang, Qingxin Xia, Steven W.M. Olde Damink, Sander S. Rensen
Citation
Xin Nie, Y. (2025). Loss of Skeletal Muscle Mass Is Associated With Reduced Cytotoxic T Cell Abundance and Poor Survival in Advanced Lung Cancer. Journal of Cachexia Sarcopenia and Muscle. https://doi.org/10.1002/jcsm.70063
Abstract
SM loss is an independent predictor for survival in patients with advanced lung cancer and is associated with reduced peripheral and tumour-infiltrating cytotoxic T cell abundance. An inadequate antitumour immune response may contribute to metabolic tissue wasting in cancer.
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