The role of physical activity, sedentary behaviour, diet, adiposity and body composition on health-related quality of life and cancer-related fatigue after diagnosis of colorectal cancer: a Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis

Georgios Markozannes, Sofia Cividini, Dagfinn Aune, Nerea Becerra‐Tomás, Š. Kiss, Katia Balducci, Rita Vieira, Margarita Cariolou, Ahmad Jayedi, Darren C. Greenwood, Nigel T. Brockton, Helen Croker, Panagiota Mitrou, Ellen Copson, Andrew G. Renehan, Martijn J.L. Bours, Wendy Demark‐Wahnefried, Melissa M. Hudson, Anne M. May, Folakemi T. Odedina, Roderick Skinner, Karen Steindorf, Anne Tjønneland, G. Velikova, Monica L. Baskin, Rajiv Chowdhury, L. Robert Hill, Sarah Lewis, Jacob C. Seidell, Matty P. Weijenberg, Jörg Krebs, Amanda J. Cross, Konstantinos K. Tsilidis, Doris S.M. Chan

Exercise and diet quality interventions might improve HRQoL and fatigue outcomes in colorectal cancer survivors. The evidence overall was limited and should be strengthened by larger, well-designed RCTs across the cancer continuum.