Infrapatellar fat pad as a source of biomarkers and therapeutic target for knee osteoarthritis

Betzabeth Pereira Herrera, Kaj S. Emanuel, Pieter J. Emans, Martijn van Griensven, Berta Cillero‐Pastor

Imaging, biochemical, and molecular studies indicate OA potential biomarkers in the IPFP related to inflammation, lipid dysregulation, and fibrosis. The combination of imaging and biochemical biomarkers could provide a better prediction of OA onset and the identification of OA progressors at an early stage. The IPFP study could also reveal potential therapeutic targets with the vision of better precision medicine.